MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody

This gene| a muscle member of the immunoglobulin gene superfamily| encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition| using a separate promoter in an intron in the 3' region| it encodes telokin| a small protein identical in sequence to the C-terminus of myosin light chain kinase| that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been

The MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of myosin light chain kinase (MLCK) phosphorylated at tyrosine 471. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody has been rigorously tested to ensure its specificity and sensitivity. It has been validated for use in a range of species, including human, mouse, and rat, and has been shown to detect endogenous levels of MLCK phosphorylated at tyrosine 471.

This antibody is supplied in a convenient 100 µg size and is provided as a lyophilized powder for ease of use and storage. It is recommended to reconstitute the antibody in sterile distilled water or PBS before use.

Overall, the MLCK(Phospho Tyr471) Rabbit Polyclonal Antibody is a reliable and effective tool for the detection of MLCK phosphorylated at tyrosine 471, making it an essential component of any researcher's toolkit.