MDC Rabbit Polyclonal Antibody

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes| dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils| eosinophils| and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) seem not be active.|online information:CCL22 entry|PTM:The N-terminal processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.|

Belongs to the intercrine beta (chemokine CC) family.|tissue specificity:Highly expressed in macrophage and in monocyte-derived dendritic cells| and thymus. Also found in lymph node| appendix| activated monocytes| resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis.|

The MDC Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of MDC protein in various biological samples. This antibody has been developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity towards MDC protein.

The MDC Rabbit Polyclonal Antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the MDC protein. The resulting antibody is purified using a combination of affinity chromatography and protein A/G purification methods, ensuring high purity and minimal cross-reactivity.

This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the MDC protein in a wide range of species, including human, mouse, and rat.

With its high specificity and sensitivity, the MDC Rabbit Polyclonal Antibody is an ideal choice for researchers studying the role of MDC protein in various biological processes. Its reliable performance and consistent results make it a valuable tool for both basic research and clinical applications.

Order the MDC Rabbit Polyclonal Antibody today and unlock new insights into the function and regulation of MDC protein in your research.