MCM3(Phospho-Ser112) Rabbit Polyclonal Antibody

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP| a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

The MCM3(Phospho-Ser112) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of MCM3 protein phosphorylated at Serine 112. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The MCM3 protein is a member of the minichromosome maintenance (MCM) protein family, which plays a crucial role in DNA replication and cell cycle progression. Phosphorylation of MCM3 at Serine 112 has been shown to regulate its function in DNA replication and cell cycle control. Therefore, the MCM3(Phospho-Ser112) Rabbit Polyclonal Antibody is an essential tool for researchers studying the molecular mechanisms of DNA replication and cell cycle regulation.

This antibody has been rigorously tested for specificity and sensitivity, ensuring reliable and reproducible results. It is supplied in a convenient format, with sufficient quantity for multiple experiments. The MCM3(Phospho-Ser112) Rabbit Polyclonal Antibody is an excellent choice for researchers seeking a high-quality antibody for the detection of phosphorylated MCM3 protein.