LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner| with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity| indicating a role as a negative regulator of CDC2/cyclin A. In addition| the C-terminal kinase domain binds to its own N-terminal region| suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

Introducing the LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the discerning needs of the scientific community. This antibody, derived from rabbits, exhibits exceptional specificity and sensitivity in detecting and quantifying the phosphorylated form of LATS1 at Thr1079.

With its unrivaled precision, this antibody serves as an invaluable tool for researchers and scientists engaged in the exploration of LATS1 signaling pathways and its intricate involvement in various cellular processes. By targeting the phosphorylated form of LATS1, this antibody enables the elucidation of critical molecular mechanisms underlying cell cycle regulation, apoptosis, and tumor suppression.

Crafted with utmost care and adherence to rigorous quality standards, this rabbit polyclonal antibody guarantees reproducibility and reliability in experimental results. Its exceptional affinity for the phosphorylated Thr1079 epitope ensures minimal cross-reactivity, thereby facilitating accurate and specific detection of LATS1 phosphorylation events.

The LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody is compatible with a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows for seamless integration into diverse experimental setups, empowering researchers to explore LATS1 signaling dynamics across various biological contexts.

Furthermore, this antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. Its long shelf life and stability guarantee optimal performance, making it an indispensable asset in any laboratory setting.

In summary, the LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody represents a pinnacle of scientific innovation, offering unparalleled specificity, sensitivity, and reliability. With its ability to unravel the intricate complexities of LATS1 signaling, this antibody serves as an indispensable tool for researchers striving to unravel the mysteries of cellular regulation and disease pathogenesis.