Kallikrein-1 Rabbit Polyclonal Antibody

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide| Lys-bradykinin| from low molecular weight kininogen.

The Kallikrein-1 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Kallikrein-1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Kallikrein-1 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The Kallikrein-1 Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and ELISA. It has been shown to specifically recognize Kallikrein-1 protein in human, mouse, and rat samples, with minimal cross-reactivity to other related proteins. The antibody exhibits high sensitivity, with a detection limit of 0.1 ng/mL in ELISA assays.

This antibody is an essential tool for researchers studying the role of Kallikrein-1 in various physiological and pathological processes, including cancer, inflammation, and cardiovascular diseases. Its high specificity and sensitivity make it an ideal reagent for the detection and quantification of Kallikrein-1 protein in biological samples. The Kallikrein-1 Rabbit Polyclonal Antibody is available in various sizes to meet the needs of different research applications.