ITGAV Rabbit Polyclonal Antibody

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1| beta 3| beta 5| beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

ITGAV Rabbit Polyclonal Antibody

The ITGAV Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of integrin alpha V (ITGAV) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ITGAV protein. The resulting polyclonal antibody exhibits high affinity and specificity towards ITGAV protein, making it an ideal tool for various applications such as western blotting, immunohistochemistry, and immunofluorescence.

The ITGAV Rabbit Polyclonal Antibody has been extensively validated for its performance and reliability in detecting ITGAV protein in a variety of biological samples, including human, mouse, and rat tissues. This antibody has been shown to exhibit minimal cross-reactivity with other integrin family members, ensuring accurate and specific detection of ITGAV protein.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using immobilized protein A. The purified antibody is provided in a liquid format, making it easy to use and store. The ITGAV Rabbit Polyclonal Antibody is suitable for use in a variety of research applications, including cancer research, cell adhesion studies, and angiogenesis research.

In summary, the ITGAV Rabbit Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of ITGAV protein in various biological samples. Its high affinity and specificity, coupled with its ease of use and reliability, make it an essential tool for researchers in the field of integrin biology.