IRS-1(Phospho-Ser302) Rabbit Polyclonal Antibody

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

The IRS-1(Phospho-Ser302) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IRS-1 protein phosphorylated at Serine 302. This antibody has been meticulously developed using advanced immunization techniques and rigorously validated to ensure optimal performance and reliability.

IRS-1, also known as Insulin Receptor Substrate 1, plays a crucial role in insulin signaling pathways and is involved in regulating glucose metabolism and cellular growth. Phosphorylation of IRS-1 at Serine 302 is a key post-translational modification that modulates its function and downstream signaling events.

This rabbit polyclonal antibody has been affinity-purified using a phospho-peptide corresponding to the phosphorylated Serine 302 region of IRS-1. It exhibits exceptional specificity towards the phosphorylated form of IRS-1, while displaying minimal cross-reactivity with non-phosphorylated IRS-1 or other related proteins.

The IRS-1(Phospho-Ser302) Rabbit Polyclonal Antibody demonstrates superior sensitivity, enabling the detection of even low levels of phosphorylated IRS-1 in various sample types, including cell lysates and tissue extracts. Its robust performance ensures accurate and reproducible results, making it an ideal choice for both qualitative and quantitative analysis of IRS-1 phosphorylation.

This antibody is supplied as a liquid formulation, ready for immediate use in various immunological techniques, such as Western blotting, immunoprecipitation, and immunofluorescence. It is compatible with a wide range of experimental conditions and has been extensively tested to ensure consistent performance across different applications.

In summary, the IRS-1(Phospho-Ser302) Rabbit Polyclonal Antibody is a reliable and highly specific tool for investigating the phosphorylation status of IRS-1 at Serine 302. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers studying insulin signaling pathways, glucose metabolism, and related cellular processes.