IRF-7(Phospho-Ser477) Rabbit Polyclonal Antibody

IRF7 encodes interferon regulatory factor 7| a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes| including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified| although the functional consequences of these have not yet been established.

The IRF-7(Phospho-Ser477) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated serine 477 residue on the interferon regulatory factor 7 (IRF-7) protein. This antibody has been meticulously developed using advanced immunization techniques and affinity purification to ensure optimal performance and reliability.

The interferon regulatory factor 7 (IRF-7) is a crucial transcription factor involved in the regulation of the immune response, particularly in the production of type I interferons. Phosphorylation of serine 477 on IRF-7 has been shown to play a critical role in its activation and subsequent induction of antiviral responses.

The IRF-7(Phospho-Ser477) Rabbit Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated serine 477 residue, enabling precise detection and quantification of this post-translational modification. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody offers outstanding sensitivity, allowing for the detection of low levels of phosphorylated IRF-7 in complex biological samples. Its high affinity ensures minimal background noise, resulting in accurate and reliable data interpretation.

The IRF-7(Phospho-Ser477) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for compatibility with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the IRF-7(Phospho-Ser477) Rabbit Polyclonal Antibody is a valuable tool for investigating the phosphorylation status of IRF-7 at serine 477. Its exceptional specificity, sensitivity, and reliability make it an essential component for researchers and clinicians studying the intricate mechanisms of immune response regulation.