Integrin alphaIIb Rabbit Polyclonal Antibody

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system| by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders| which are characterized by a failure of platelet aggregation| including Glanzmann thrombasthenia.

The Integrin alphaIIb Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Integrin alphaIIb protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Integrin alphaIIb protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The Integrin alphaIIb Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody has been shown to specifically recognize Integrin alphaIIb protein in human, mouse, and rat samples, making it a versatile tool for researchers studying Integrin alphaIIb function and regulation.

The Integrin alphaIIb Rabbit Polyclonal Antibody is a valuable tool for researchers studying platelet function, thrombosis, and hemostasis. This antibody can be used to investigate the role of Integrin alphaIIb in platelet aggregation and clot formation, as well as its potential as a therapeutic target for the treatment of thrombotic disorders. Additionally, this antibody may be useful for the development of diagnostic assays for the detection of Integrin alphaIIb in patient samples.

In summary, the Integrin alphaIIb Rabbit Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of Integrin alphaIIb protein in various biological samples. Its versatility and reliability make it a valuable tool for researchers studying platelet function, thrombosis, and hemostasis.