INT3 Rabbit Polyclonal Antibody

The protein encoded by this gene can form a complex with human single-strand DNA binding proteins 1 or 2 (hSSB1 and hSSB2) and other proteins to mediate genome stability and the DNA damage response. The encoded protein is also part of a multiprotein complex that interacts with the C-terminal domain of RNA polymerase II large subunit to help regulate processing of U1 and U2 small nuclear RNAs.

The INT3 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of INT3 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the INT3 protein.

The INT3 protein, also known as integrator complex subunit 3, plays a crucial role in RNA processing and transcriptional regulation. It is involved in the 3'-end processing of small nuclear RNAs and the integration of small nuclear RNA into the mature RNA molecule. Dysregulation of INT3 has been implicated in various diseases, including cancer and neurodegenerative disorders.

The INT3 Rabbit Polyclonal Antibody exhibits high affinity and specificity towards the INT3 protein, ensuring accurate and reliable results in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications. It recognizes both the native and denatured forms of the INT3 protein, allowing for versatile experimental approaches.

This antibody has been extensively validated in various cell lines and tissue samples, demonstrating its robust performance and consistent staining patterns. It exhibits minimal cross-reactivity with other proteins, ensuring specific detection of INT3 protein expression.

The INT3 Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size of 100 μg, ensuring ample quantity for multiple experiments. The antibody is stored at -20°C to maintain its stability and activity.

In summary, the INT3 Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of INT3 protein expression. Its high specificity, sensitivity, and versatility make it an ideal choice for researchers studying RNA processing, transcriptional regulation, and related diseases.