Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway| which regulates glucose uptake and release| as well as the synthesis and storage of carbohydrates| lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome| Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

The Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphorylated tyrosine residue 1345 on the insulin receptor beta subunit. This antibody is produced using high-quality rabbit polyclonal antibodies and is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The Insulin Receptor beta(Phospho-Tyr1345) Rabbit Polyclonal Antibody is an essential tool for researchers studying insulin signaling pathways and related diseases, such as diabetes and metabolic disorders. With its superior specificity and sensitivity, this antibody is an ideal choice for accurate and reliable detection of phosphorylated insulin receptor beta subunit in various biological samples.