HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Introducing the HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody, a highly specialized and meticulously developed product designed to facilitate advanced research in the field of molecular biology. This antibody, derived from rabbit polyclonal sources, has been specifically engineered to target and detect the phosphorylated serine residue at position 247 of the hepatocyte nuclear factor 1 alpha (HNF1α) protein.

With its exceptional specificity and sensitivity, this antibody offers researchers an invaluable tool for investigating the intricate signaling pathways and regulatory mechanisms involving HNF1α. By selectively binding to the phosphorylated serine residue at position 247, this antibody enables the precise identification and quantification of HNF1α phosphorylation events, thereby shedding light on its functional implications in various cellular processes.

The HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody has undergone rigorous quality control measures to ensure optimal performance and reliability. Its high affinity for the phosphorylated serine residue, coupled with its low background noise, guarantees accurate and reproducible results. Furthermore, this antibody exhibits excellent cross-reactivity, enabling its application across a wide range of species and experimental conditions.

This product is supplied in a convenient and user-friendly format, allowing for easy integration into existing laboratory protocols. Its compatibility with various immunological techniques, including Western blotting, immunohistochemistry, and immunofluorescence, further enhances its versatility and applicability in diverse research settings.

In summary, the HNF1 alpha(Phospho-Ser247) Rabbit Polyclonal Antibody represents a cutting-edge solution for investigating the phosphorylation dynamics of HNF1α. Its exceptional specificity, sensitivity, and reliability make it an indispensable tool for elucidating the intricate molecular mechanisms underlying cellular processes. Researchers can confidently rely on this antibody to advance their understanding of HNF1α-mediated signaling pathways and contribute to the progress of molecular biology research.