HMGN1/2/3/4 (Acetyl Lys27/K33/K31) Rabbit Polyclonal Antibody

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein| HMG17| the encoded protein may help maintain an open chromatin configuration around transcribable genes.

The HMGN1/2/3/4 (Acetyl Lys27/K33/K31) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of HMGN1/2/3/4 proteins in various biological samples. This antibody is produced by immunizing rabbits with synthetic peptides corresponding to the acetylated lysine residues at positions 27, 33, and 31 of the HMGN1/2/3/4 proteins. The resulting polyclonal antibody exhibits high affinity and specificity towards the acetylated forms of HMGN1/2/3/4, making it an ideal tool for studying the role of these proteins in chromatin structure and gene expression regulation.

The HMGN1/2/3/4 (Acetyl Lys27/K33/K31) Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunoprecipitation, and immunofluorescence microscopy. It has been shown to detect endogenous levels of acetylated HMGN1/2/3/4 proteins in various cell lines and tissues, and can be used to monitor changes in their expression levels under different experimental conditions.

This antibody is supplied as a purified IgG fraction, and has been affinity-purified using immobilized acetylated peptides to ensure maximum specificity and minimal cross-reactivity with non-acetylated forms of HMGN1/2/3/4. It is provided in a convenient 100 µg size, and is suitable for use in both basic research and clinical applications.

Overall, the HMGN1/2/3/4 (Acetyl Lys27/K33/K31) Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can be used to study the function and regulation of HMGN1/2/3/4 proteins in various biological systems. Its high specificity and sensitivity make it an essential tool for researchers working in the fields of chromatin biology, gene expression regulation, and epigenetics.