HMG-I/HMG-Y (Acetyl Lys65) Rabbit Polyclonal Antibody

This gene encodes a chromatin-associated protein involved in the regulation of gene transcription| integration of retroviruses into chromosomes| and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes.

The HMG-I/HMG-Y (Acetyl Lys65) Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of HMG-I/HMG-Y proteins in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the acetylated lysine 65 of HMG-I/HMG-Y protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the acetylated form of HMG-I/HMG-Y protein, making it an ideal tool for studying the post-translational modifications of this protein.

The HMG-I/HMG-Y (Acetyl Lys65) Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It has been shown to detect endogenous levels of acetylated HMG-I/HMG-Y protein in various cell lines and tissues, and can be used to monitor changes in protein expression and modification under different experimental conditions.

This antibody is supplied as a purified IgG fraction, and has been affinity-purified using immobilized acetylated lysine peptide. It is provided in a liquid format, and can be stored at -20°C for long-term use. The HMG-I/HMG-Y (Acetyl Lys65) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of HMG-I/HMG-Y protein in various biological processes, including gene regulation, DNA repair, and cancer development.