Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes.

The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Introducing the Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of molecular biology. This antibody, derived from rabbits, exhibits exceptional specificity and sensitivity, making it an invaluable tool for the investigation of histone H2B phosphorylation at the serine 14 residue.

With its superior affinity and selectivity, this polyclonal antibody enables precise detection and quantification of the phosphorylated form of histone H2B, facilitating a deeper understanding of the intricate mechanisms underlying cellular processes such as gene expression, DNA repair, and chromatin remodeling. Its robust performance ensures reliable and reproducible results, empowering researchers to unravel the complexities of epigenetic regulation with utmost confidence.

The Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody has been rigorously validated through various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional specificity is further enhanced by its minimal cross-reactivity with non-phosphorylated histone H2B, ensuring accurate and unambiguous detection of the phosphorylated form.

This antibody is supplied in a convenient and user-friendly format, allowing for easy integration into existing laboratory protocols. Its high-quality formulation guarantees long-term stability and reliability, ensuring consistent performance throughout the duration of experiments. Additionally, it is compatible with a wide range of sample types, including cell lysates, tissue sections, and cultured cells, providing versatility and flexibility in experimental design.

In summary, the Histone H2B(Phospho-Ser14) Rabbit Polyclonal Antibody represents a cutting-edge solution for researchers seeking to delve into the intricate world of histone H2B phosphorylation. Its exceptional specificity, sensitivity, and reliability make it an indispensable tool for unraveling the complexities of epigenetic regulation and advancing scientific knowledge in the field of molecular biology.