Histone H2B (Acetyl Lys86) Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A| H2B| H3| and H4).

The chromatin fiber is further compacted through the interaction of a linker histone| H1| with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead| they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H2B (Acetyl Lys86) Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Histone H2B protein acetylated at Lysine 86. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

Histone H2B is a crucial component of the nucleosome, playing a vital role in chromatin structure and gene regulation. Acetylation of Lysine 86 on Histone H2B has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the Histone H2B (Acetyl Lys86) Rabbit Polyclonal Antibody serves as an invaluable tool for researchers studying epigenetic modifications and their impact on gene expression.

This antibody exhibits outstanding performance in a wide range of species, including human, mouse, and rat, making it suitable for diverse experimental settings. Its high affinity and specificity ensure minimal cross-reactivity with non-acetylated forms of Histone H2B, enabling accurate and reliable detection of the acetylated protein.

The Histone H2B (Acetyl Lys86) Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 100 µg size, ensuring an ample amount for multiple experiments. The antibody has been rigorously validated and quality-controlled to ensure consistent and reproducible results.

In summary, the Histone H2B (Acetyl Lys86) Rabbit Polyclonal Antibody is a superior research tool that offers exceptional sensitivity, specificity, and versatility. Its reliable performance and broad applicability make it an indispensable asset for scientists investigating the intricate mechanisms of epigenetic regulation and gene expression.