Histone H2B (Acetyl Lys17) Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A| H2B| H3| and H4).

The chromatin fiber is further compacted through the interaction of a linker histone| H1| with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

The Histone H2B (Acetyl Lys17) Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Histone H2B acetylated at Lysine 17. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation (ChIP).

Histone H2B is a crucial component of nucleosomes, playing a vital role in chromatin structure and gene regulation. Acetylation of Lysine 17 on Histone H2B has been implicated in transcriptional activation and is associated with active gene expression. Therefore, the Histone H2B (Acetyl Lys17) Rabbit Polyclonal Antibody serves as an invaluable tool for investigating epigenetic modifications and their impact on gene regulation.

This antibody has been extensively validated and exhibits exceptional performance in various experimental conditions. It demonstrates high specificity, minimal cross-reactivity, and negligible background noise, ensuring accurate and reliable results. Additionally, it exhibits excellent sensitivity, allowing for the detection of low-abundance acetylated Histone H2B species.

The Histone H2B (Acetyl Lys17) Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy storage and handling. Each batch of antibody undergoes rigorous quality control procedures to ensure consistent performance and batch-to-batch reproducibility.

In summary, the Histone H2B (Acetyl Lys17) Rabbit Polyclonal Antibody is a reliable and specific tool for the detection and analysis of Histone H2B acetylated at Lysine 17. Its exceptional sensitivity, specificity, and ease of use make it an ideal choice for researchers studying epigenetic modifications and their impact on gene regulation.