H2B2E Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes.

The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family| and generates two transcripts through the use of the conserved stem-loop termination motif| and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

The H2B2E Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of histone H2B2E protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human histone H2B2E protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for a wide range of applications in research and diagnostics.

The H2B2E Rabbit Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other histone H2B isoforms. This antibody is supplied as a purified IgG fraction, and has been conjugated with horseradish peroxidase (HRP) for easy detection and visualization.

In summary, the H2B2E Rabbit Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of histone H2B2E protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians working in the fields of epigenetics, cancer biology, and developmental biology.