H11 Rabbit Polyclonal Antibody

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes.

The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

The H11 Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of target proteins in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.

The H11 Rabbit Polyclonal Antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to exhibit excellent sensitivity and specificity, with minimal cross-reactivity to non-target proteins.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to suit different experimental needs.

The H11 Rabbit Polyclonal Antibody is an ideal tool for researchers studying protein expression and function in various biological systems. Its high specificity and sensitivity make it a valuable asset for a wide range of applications, including basic research, drug discovery, and clinical diagnostics. With its reliable performance and consistent quality, this antibody is a trusted choice for scientists worldwide.