GSTM5 Rabbit Polyclonal Antibody

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present| eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha| kappa| mu| omega| pi| sigma| theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione.

The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains| as well as in tissue expression patterns| to accommodate an increasing number of foreign compounds.

The GSTM5 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of Glutathione S-transferase Mu 5 (GSTM5) protein. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and sensitivity towards GSTM5.

The GSTM5 Rabbit Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables accurate and precise identification of GSTM5 protein expression in a wide range of samples, such as cell lysates, tissue sections, and whole organisms.

With its superior specificity, this antibody ensures minimal cross-reactivity with other related proteins, thereby providing reliable and reproducible results. Its robustness and consistency make it an ideal choice for both research and diagnostic purposes.

The GSTM5 Rabbit Polyclonal Antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. It is supplied in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

In summary, the GSTM5 Rabbit Polyclonal Antibody is a valuable tool for researchers and clinicians alike, offering exceptional sensitivity, specificity, and ease of use. Its application versatility and reliable performance make it an indispensable asset in the study of GSTM5 protein expression and its implications in various biological processes and diseases.