FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

The FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FoxO3a protein phosphorylated at Serine 318 and 321 residues. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The FoxO3a protein plays a crucial role in regulating cellular processes such as cell cycle progression, apoptosis, and oxidative stress response. Phosphorylation of FoxO3a at Serine 318 and 321 residues is known to modulate its activity and subcellular localization, making it an important target for studying cellular signaling pathways and disease mechanisms.

This antibody has been rigorously validated for its specificity and sensitivity, ensuring accurate and reproducible results. It exhibits minimal cross-reactivity with non-phosphorylated FoxO3a protein, enabling precise detection of the phosphorylated form. Additionally, it demonstrates minimal background staining, allowing for clear visualization of the target protein in complex biological samples.

The FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into various experimental protocols. The antibody has been optimized for use in a wide range of species, including human, mouse, and rat, making it suitable for diverse research applications.

In summary, the FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody is a reliable and versatile tool for investigating the phosphorylation status of FoxO3a protein. Its high specificity, sensitivity, and ease of use make it an essential reagent for researchers studying cellular signaling pathways, disease mechanisms, and therapeutic interventions.