FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody

disease:A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. Translocation t(6;11)(q21;q23) with MLL/HRX.|Transcriptional activator which triggers apoptosis in the absence of survival factors| including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-

The FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of FoxO3A protein in various biological samples. This antibody has been developed using a rabbit polyclonal approach, ensuring high affinity and sensitivity towards the target protein.

The FoxO3A protein, a member of the Forkhead box O (FoxO) transcription factor family, plays a crucial role in regulating various cellular processes, including cell cycle arrest, apoptosis, and oxidative stress response. The acetylation of Lys569 residue in FoxO3A has been shown to modulate its transcriptional activity and subcellular localization, making it an important post-translational modification for studying FoxO3A function.

This antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other FoxO family members, ensuring accurate and reliable results.

The FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use in various applications, including immunohistochemistry, flow cytometry, and chromatin immunoprecipitation. It is provided in a convenient size of 100 µg, ensuring ample supply for multiple experiments.

With its high specificity, sensitivity, and versatility, the FoxO3A (Acetyl Lys569) Rabbit Polyclonal Antibody is an essential tool for researchers studying the role of FoxO3A in cellular processes and its potential implications in various diseases, including cancer, neurodegenerative disorders, and aging.