FLT3(Phospho-Tyr591) Rabbit Polyclonal Antibody

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain| which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis| proliferation| and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

The FLT3(Phospho-Tyr591) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FLT3 protein phosphorylated at tyrosine 591. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reproducibility.

FLT3, also known as FMS-like tyrosine kinase 3, is a receptor tyrosine kinase that plays a crucial role in hematopoiesis and immune system development. Phosphorylation of FLT3 at tyrosine 591 is known to regulate its activity and downstream signaling pathways, making it an important target for research in various fields, including cancer biology and immunology.

The FLT3(Phospho-Tyr591) Rabbit Polyclonal Antibody has been rigorously validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. Each batch of the FLT3(Phospho-Tyr591) Rabbit Polyclonal Antibody undergoes strict quality control measures to ensure consistent performance and batch-to-batch reproducibility.

In summary, the FLT3(Phospho-Tyr591) Rabbit Polyclonal Antibody is a valuable tool for researchers studying FLT3 signaling and its role in various biological processes. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate and reproducible detection and quantification of phosphorylated FLT3 at tyrosine 591.