FKHRL1(Phospho Ser315) Rabbit Polyclonal Antibody

disease:A chromosomal aberration involving FOXO3 is found in secondary acute leukemias. Translocation t(6;11)(q21;q23) with MLL/HRX.|Transcriptional activator which triggers apoptosis in the absence of survival factors| including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-

The FKHRL1(Phospho Ser315) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FKHRL1 protein phosphorylated at Ser315. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The FKHRL1 protein, also known as FOXO3a, plays a crucial role in regulating cell cycle progression, apoptosis, and oxidative stress response. Phosphorylation of FKHRL1 at Ser315 is a key post-translational modification that modulates its transcriptional activity and subcellular localization. Therefore, the ability to accurately detect and measure the phosphorylation status of FKHRL1 is of utmost importance in understanding its functional implications in various biological processes.

This rabbit polyclonal antibody has been raised against a synthetic peptide corresponding to the phosphorylated region of FKHRL1 at Ser315. It exhibits high specificity towards the phosphorylated form of FKHRL1 and shows minimal cross-reactivity with non-phosphorylated FKHRL1 or other related proteins. The antibody has been extensively validated using both positive and negative controls to ensure its specificity and sensitivity.

The FKHRL1(Phospho Ser315) Rabbit Polyclonal Antibody offers numerous advantages for researchers in the field of cell biology and molecular biology. Its high affinity and specificity enable accurate detection and quantification of phosphorylated FKHRL1 in various sample types, including cell lysates, tissue extracts, and cultured cells. The antibody exhibits excellent signal-to-noise ratio, allowing for precise and reliable quantification of FKHRL1 phosphorylation levels.

Furthermore, this antibody has been optimized for use in multiple applications. It performs exceptionally well in Western blotting, producing clear and distinct bands at the appropriate molecular weight. In immunohistochemistry, it enables precise localization of phosphorylated FKHRL1 within tissue sections, providing valuable insights into its spatial distribution. Additionally, the antibody can be used in immunofluorescence experiments to visualize the subcellular localization of phosphorylated FKHRL1 with high resolution.

In summary, the FKHRL1(Phospho Ser315) Rabbit Polyclonal Antibody is a highly reliable and versatile tool for the detection and quantification of phosphorylated FKHRL1 protein. Its exceptional specificity, sensitivity, and performance in various applications make it an invaluable asset for researchers aiming to elucidate