BT Lab
SKU:BT-AP02646
FBX22 Rabbit Polyclonal Antibody
FBX22 Rabbit Polyclonal Antibody
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and| as a transcriptional target of the tumor protein p53| is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.
The FBX22 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of FBX22 protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity in immunohistochemistry (IHC), immunofluorescence (IF), and western blot (WB) applications.
FBX22 is a member of the F-box protein family, which plays a crucial role in the regulation of protein degradation through the ubiquitin-proteasome system. FBX22 has been implicated in various cellular processes, including cell cycle progression, DNA damage response, and cellular differentiation. Its dysregulation has been associated with several diseases, making it an important target for research and diagnostic purposes.
The FBX22 Rabbit Polyclonal Antibody exhibits excellent performance in detecting endogenous levels of FBX22 protein in a wide range of species, including human, mouse, and rat. It has been rigorously validated to ensure minimal cross-reactivity with other proteins, ensuring accurate and reliable results. With its high affinity and specificity, this antibody enables precise localization and quantification of FBX22 protein expression in tissues and cells.
This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy customization and optimization of experimental conditions. The FBX22 Rabbit Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results from batch to batch.
In summary, the FBX22 Rabbit Polyclonal Antibody is a valuable tool for researchers and clinicians involved in studying FBX22 protein expression and its role in various biological processes. Its exceptional sensitivity, specificity, and versatility make it an indispensable asset in the field of molecular biology and biomedical research.
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