FA9 Rabbit Polyclonal Antibody

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa| which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions| membrane phospholipids| and factor VIII. Alterations of this gene| including point mutations| insertions and deletions| cause factor IX deficiency| which is a recessive X-linked disorder| also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

The FA9 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the human coagulation factor IX (FA9) protein. The FA9 Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting FA9 protein in various biological samples.

The FA9 Rabbit Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and ELISA. It has been shown to specifically recognize FA9 protein in human, mouse, and rat samples. This antibody has a high affinity for its target protein, allowing for reliable and accurate detection of FA9 protein in even low abundance samples.

The FA9 Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum. It is provided in a convenient format, with a concentration of 1 mg/mL, making it easy to use in a variety of applications. This antibody has been rigorously tested for its quality and performance, ensuring that it meets the highest standards of research.

Overall, the FA9 Rabbit Polyclonal Antibody is a reliable and sensitive tool for the detection of FA9 protein in various research applications. Its high specificity and sensitivity make it an ideal choice for researchers studying coagulation factor IX and its role in various biological processes.