FA11 Rabbit Polyclonal Antibody

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

The FA11 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various immunohistochemical applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein. It has been extensively validated for its specificity and sensitivity in detecting the target protein in various tissues and cell types.

The FA11 Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards its target protein, ensuring accurate and reproducible results. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing reliable and specific staining.

This antibody is suitable for use in a wide range of research applications, including immunohistochemistry, immunofluorescence, and Western blotting. It can be used to study the expression and localization of the target protein in various biological samples, aiding in the understanding of its role in physiological and pathological processes.

The FA11 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The antibody is available in different sizes to accommodate various experimental needs.

With its exceptional specificity, sensitivity, and ease of use, the FA11 Rabbit Polyclonal Antibody is an invaluable tool for researchers in the field of immunohistochemistry. Its reliable performance and consistent results make it an ideal choice for studying the target protein in diverse biological contexts.