Ezh2(Phospho-Thr311) Rabbit Polyclonal Antibody

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes| which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein| the VAV1 oncoprotein| and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

The Ezh2(Phospho-Thr311) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Ezh2 protein phosphorylated at Thr311 residue. This antibody has been meticulously developed using advanced immunization techniques and rigorously validated to ensure optimal performance and reliability.

Ezh2, also known as Enhancer of Zeste Homolog 2, is a crucial component of the Polycomb Repressive Complex 2 (PRC2) and plays a pivotal role in epigenetic regulation. Phosphorylation of Ezh2 at Thr311 has been implicated in various biological processes, including cell proliferation, differentiation, and tumorigenesis. Therefore, the ability to accurately measure the phosphorylation status of Ezh2 at Thr311 is of utmost importance in understanding its functional significance and its involvement in disease progression.

This rabbit polyclonal antibody has been affinity-purified using a phospho-peptide corresponding to the phosphorylated Thr311 region of Ezh2 protein. It exhibits exceptional specificity towards the phosphorylated form of Ezh2 and shows minimal cross-reactivity with non-phosphorylated Ezh2 or other related proteins. The high sensitivity of this antibody allows for the detection of even low levels of phosphorylated Ezh2, making it an ideal tool for both qualitative and quantitative analysis.

The Ezh2(Phospho-Thr311) Rabbit Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively tested on a wide range of sample types, including cell lysates, tissue sections, and cultured cells, ensuring its versatility and reliability across different experimental setups.

In summary, the Ezh2(Phospho-Thr311) Rabbit Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and quantification of phosphorylated Ezh2 at Thr311 residue. Its exceptional performance, reliability, and versatility make it an invaluable asset for researchers studying the role of Ezh2 phosphorylation in various biological processes and disease states.