EPHA3(Phospho Tyr602) Rabbit Polyclonal Antibody

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events| particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.

The EPHA3(Phospho Tyr602) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of EPHA3 protein phosphorylated at tyrosine 602 residue. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The EPHA3 receptor tyrosine kinase plays a crucial role in various cellular processes, including cell adhesion, migration, and proliferation. Phosphorylation of the tyrosine 602 residue is known to regulate the activation and downstream signaling of EPHA3, making it an important target for research in cancer biology, neurobiology, and developmental biology.

This EPHA3(Phospho Tyr602) Rabbit Polyclonal Antibody has been rigorously validated for its specificity and sensitivity, ensuring accurate and reproducible results. It exhibits minimal cross-reactivity with other phosphorylated tyrosine residues, ensuring reliable detection of EPHA3 phosphorylated at tyrosine 602.

With its high affinity and specificity, this antibody enables researchers to investigate the role of EPHA3 phosphorylation in various biological processes and disease states. Its versatility allows for the detection of EPHA3(Phospho Tyr602) in a wide range of sample types, including cell lysates, tissue extracts, and formalin-fixed paraffin-embedded (FFPE) sections.

In summary, the EPHA3(Phospho Tyr602) Rabbit Polyclonal Antibody is a valuable tool for researchers studying EPHA3 signaling pathways and its role in various biological processes. Its high specificity, sensitivity, and versatility make it an essential component of any research project aiming to elucidate the molecular mechanisms underlying EPHA3 function.