EphA2(Phospho-Ser897) Rabbit Polyclonal Antibody

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events| particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.

The EphA2(Phospho-Ser897) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of EphA2 protein phosphorylated at serine 897. This antibody has been rigorously validated for its specificity and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The EphA2 receptor plays a crucial role in cell signaling and is involved in various cellular processes, such as cell adhesion, migration, and proliferation. Phosphorylation of EphA2 at serine 897 has been shown to regulate its activity and downstream signaling pathways. Therefore, the ability to specifically detect and quantify this phosphorylation event is of great importance in understanding the functional role of EphA2 in various biological contexts.

This rabbit polyclonal antibody has been generated using a highly purified phospho-peptide corresponding to the phosphorylated serine 897 of EphA2. It exhibits high affinity and specificity towards the phosphorylated form of EphA2, while showing minimal cross-reactivity with non-phosphorylated EphA2 or other related proteins.

The EphA2(Phospho-Ser897) Rabbit Polyclonal Antibody has been extensively tested and validated using a variety of cell lysates and tissue samples. It demonstrates excellent sensitivity, allowing for the detection of even low levels of phosphorylated EphA2. Furthermore, it exhibits minimal background signal, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The EphA2(Phospho-Ser897) Rabbit Polyclonal Antibody is an essential tool for researchers studying EphA2 signaling and its role in various physiological and pathological processes.