EGF Receptor(Phospho-Tyr1045) Rabbit Polyclonal Antibody

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

The EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of the phosphorylated tyrosine 1045 residue on the epidermal growth factor receptor (EGFR). This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reproducibility in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The phosphorylation of tyrosine 1045 on the EGFR plays a crucial role in the regulation of EGFR signaling pathways, which are involved in cell proliferation, differentiation, and survival. By targeting this specific phosphorylation site, the EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody enables researchers to investigate the activation status of EGFR and its downstream signaling cascades.

This antibody exhibits exceptional sensitivity and specificity, allowing for the detection of even low levels of phosphorylated EGFR in complex biological samples. It has been extensively validated in various cell lines and tissues, ensuring reliable and accurate results. Additionally, the antibody has been rigorously tested for cross-reactivity with other phosphorylated tyrosine residues and non-phosphorylated EGFR, ensuring its specificity for the phosphorylated tyrosine 1045 residue.

The EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is provided in a convenient size, allowing for multiple experiments without wastage. The antibody is also compatible with a wide range of secondary detection systems, facilitating its integration into existing experimental protocols.

In summary, the EGF Receptor (Phospho-Tyr1045) Rabbit Polyclonal Antibody is a reliable and versatile tool for the investigation of EGFR signaling pathways. Its high specificity, sensitivity, and ease of use make it an essential component of any research project focused on understanding the role of EGFR phosphorylation in cellular processes.