DTNA Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC)| which consists of dystrophin and several integral and peripheral membrane proteins| including dystroglycans| sarcoglycans| syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

The DTNA Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of dystrobrevin alpha (DTNA) protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human DTNA protein. The resulting polyclonal antibody exhibits high affinity and specificity towards DTNA protein, making it an ideal tool for various research applications.

The DTNA Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays. It has been shown to detect DTNA protein in a variety of tissues and cell lines, including heart, skeletal muscle, and brain. This antibody is also suitable for use in other applications, such as ELISA and flow cytometry.

The DTNA Rabbit Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using DTNA protein as the immunogen. It is provided in a liquid format, ready to use for various applications. The antibody is also available in different sizes and formats to meet the specific needs of researchers.

In summary, the DTNA Rabbit Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of DTNA protein in various biological samples. Its high affinity and specificity make it an essential tool for researchers studying the role of DTNA protein in various physiological and pathological processes.