NFATc1(Phospho Ser294) Polyclonal Antibody

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation| and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

The NFATc1(Phospho Ser294) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of NFATc1 protein phosphorylated at Ser294. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

NFATc1, also known as nuclear factor of activated T-cells cytoplasmic 1, is a transcription factor that plays a crucial role in the regulation of immune response and cell differentiation. Phosphorylation of NFATc1 at Ser294 has been shown to be involved in its activation and nuclear translocation, leading to the modulation of gene expression.

The NFATc1(Phospho Ser294) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated NFATc1 and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term use to maintain its stability and activity.

In summary, the NFATc1(Phospho Ser294) Polyclonal Antibody is a valuable tool for researchers studying NFATc1 signaling pathways and its role in various biological processes. Its high specificity, sensitivity, and reliability make it an essential component in any laboratory focused on immunological and cellular research.