DDR1(Phospho-Tyr792) Rabbit Polyclonal Antibody

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth| differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain| and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells| particularly in the kidney| lung| gastrointestinal tract| and brain. In addition| it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

The DDR1(Phospho-Tyr792) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of DDR1 protein phosphorylated at tyrosine 792. This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The DDR1 protein, also known as discoidin domain receptor 1, plays a crucial role in cell adhesion, migration, and invasion. Phosphorylation of DDR1 at tyrosine 792 is a key event in the activation of downstream signaling pathways involved in these cellular processes. Therefore, the ability to specifically detect and quantify phosphorylated DDR1 at this site is of utmost importance in understanding the functional implications of DDR1 signaling.

Our DDR1(Phospho-Tyr792) Rabbit Polyclonal Antibody has been developed using high-quality rabbit polyclonal antibodies that exhibit exceptional specificity and sensitivity towards phosphorylated DDR1 at tyrosine 792. The antibody has been extensively characterized and validated using various experimental approaches, ensuring reliable and reproducible results.

This antibody is suitable for use in a wide range of applications, including Western blotting, where it can be used to detect the presence and relative abundance of phosphorylated DDR1 in cell lysates or tissue samples. It can also be used for immunoprecipitation, allowing for the isolation and enrichment of phosphorylated DDR1 from complex protein mixtures. Additionally, the antibody can be utilized in immunofluorescence experiments to visualize the subcellular localization of phosphorylated DDR1 in fixed cells.

In summary, the DDR1(Phospho-Tyr792) Rabbit Polyclonal Antibody is a valuable tool for researchers studying DDR1 signaling and its role in cellular processes. Its high specificity, sensitivity, and versatility make it an essential component of any study aiming to elucidate the functional implications of DDR1 phosphorylation.