IKK gamma(Phospho Ser376) Polyclonal Antibody

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex| which activates NF-kappaB resulting in activation of genes involved in inflammation| immunity| cell survival| and other pathways. Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

The IKK gamma(Phospho Ser376) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of IKK gamma protein phosphorylated at Ser376. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

IKK gamma, also known as NEMO (NF-κB essential modulator), plays a crucial role in the activation of the NF-κB signaling pathway. Phosphorylation of IKK gamma at Ser376 has been shown to regulate its function and downstream signaling events. Therefore, the IKK gamma(Phospho Ser376) Polyclonal Antibody is an invaluable tool for researchers studying the NF-κB pathway and its associated cellular processes.

This antibody has been extensively validated for various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IKK gamma in complex biological samples.

The IKK gamma(Phospho Ser376) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and reliability, the IKK gamma(Phospho Ser376) Polyclonal Antibody is an essential tool for researchers investigating the intricate mechanisms of the NF-κB signaling pathway and its involvement in various physiological and pathological processes.