IKK gamma(Phospho Ser31) Polyclonal Antibody

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex| which activates NF-kappaB resulting in activation of genes involved in inflammation| immunity| cell survival| and other pathways. Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

The IKK gamma(Phospho Ser31) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of IKK gamma protein phosphorylated at Ser31. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The IKK gamma protein plays a crucial role in the regulation of various cellular processes, including immune response, inflammation, and cell survival. Phosphorylation of IKK gamma at Ser31 has been implicated in the activation of the NF-kappaB signaling pathway, which is involved in the transcriptional regulation of genes associated with immune and inflammatory responses.

This polyclonal antibody is generated by immunizing animals with a synthetic phospho-peptide corresponding to the region surrounding Ser31 of the IKK gamma protein. It has been extensively validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence.

The IKK gamma(Phospho Ser31) Polyclonal Antibody exhibits excellent performance in detecting endogenous levels of phosphorylated IKK gamma protein in various cell and tissue lysates. It demonstrates minimal cross-reactivity with non-phosphorylated IKK gamma protein, ensuring accurate and reliable results.

With its high specificity and sensitivity, the IKK gamma(Phospho Ser31) Polyclonal Antibody is an invaluable tool for researchers studying the NF-kappaB signaling pathway and its involvement in immune response and inflammation. It provides a reliable means of investigating the phosphorylation status of IKK gamma protein and its functional implications in various biological processes.

In summary, the IKK gamma(Phospho Ser31) Polyclonal Antibody is a top-quality research reagent that offers exceptional performance and reliability. Its specificity, sensitivity, and versatility make it an essential tool for scientists and researchers in the field of molecular biology, immunology, and related disciplines.