DAZL Rabbit Polyclonal Antibody

The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis| this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

The DAZL Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of DAZL protein expression in various biological samples. This antibody is produced using a rabbit host and has been rigorously validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and Western blotting applications.

The DAZL Rabbit Polyclonal Antibody exhibits a high affinity towards DAZL protein, enabling reliable and accurate detection even at low expression levels. Its exceptional specificity ensures minimal cross-reactivity with other proteins, guaranteeing precise and reliable results. This antibody is suitable for use in a wide range of species, including human, mouse, rat, and other mammalian species.

With its robust and versatile nature, the DAZL Rabbit Polyclonal Antibody offers researchers a valuable tool for investigating the role of DAZL protein in various biological processes, such as germ cell development, meiosis, and fertility. Its application in IHC allows for the visualization and localization of DAZL protein within tissues, providing valuable insights into its cellular distribution and function.

Furthermore, the DAZL Rabbit Polyclonal Antibody can be utilized in IF experiments to study the subcellular localization of DAZL protein, enabling researchers to gain a deeper understanding of its involvement in cellular processes. Additionally, its compatibility with Western blotting allows for the quantification of DAZL protein expression levels, facilitating comparative analysis and further elucidation of its biological significance.

The DAZL Rabbit Polyclonal Antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is provided in various sizes to accommodate different experimental requirements.

In summary, the DAZL Rabbit Polyclonal Antibody is a reliable and versatile tool for the detection and quantification of DAZL protein expression. Its exceptional specificity, sensitivity, and compatibility with multiple applications make it an invaluable asset for researchers studying the role of DAZL protein in various biological processes.