DAB2 Rabbit Polyclonal Antibody

This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells| but is down-regulated or absent from ovarian carcinoma cell lines| suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

The DAB2 Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of DAB2 protein expression in various biological samples. This antibody has been rigorously tested and validated to ensure its reliability and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

The DAB2 Rabbit Polyclonal Antibody exhibits exceptional affinity and specificity towards the DAB2 protein, enabling precise and reliable detection of its expression levels. It has been designed and produced using advanced recombinant DNA technology, ensuring high purity and consistency in every batch.

This antibody offers exceptional sensitivity, allowing for the detection of even low levels of DAB2 protein expression. Its high specificity ensures minimal cross-reactivity with other proteins, resulting in accurate and reliable results. The DAB2 Rabbit Polyclonal Antibody is suitable for use in a wide range of biological samples, including tissue sections, cell lysates, and whole-cell extracts.

In addition to its exceptional performance, this antibody is also highly versatile and compatible with various experimental techniques. It can be used in immunohistochemistry to visualize the localization and distribution of DAB2 protein in tissue sections. Furthermore, it can be employed in immunofluorescence assays to study the subcellular localization of DAB2 protein in cultured cells. Additionally, it can be utilized in western blotting to analyze the expression levels of DAB2 protein in different samples.

The DAB2 Rabbit Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. This antibody is available in various sizes to accommodate different experimental needs.

Overall, the DAB2 Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of DAB2 protein expression. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers in the fields of molecular biology, cell biology, and biomedical research.