IGFBP3(Phospho Ser183) Polyclonal Antibody

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants| encoding different isoforms| have been characterized.

The IGFBP3(Phospho Ser183) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IGFBP3 protein phosphorylated at Ser183. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

IGFBP3, also known as insulin-like growth factor-binding protein 3, plays a crucial role in regulating the bioavailability and activity of insulin-like growth factors (IGFs). Phosphorylation of IGFBP3 at Ser183 has been implicated in various cellular processes, including cell proliferation, differentiation, and apoptosis.

The IGFBP3(Phospho Ser183) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IGFBP3 in various biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The IGFBP3(Phospho Ser183) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

With its exceptional performance and reliability, the IGFBP3(Phospho Ser183) Polyclonal Antibody is an indispensable tool for researchers and scientists studying the role of IGFBP3 phosphorylation in various physiological and pathological processes.