IGF-IR(Phospho Tyr1161) Polyclonal Antibody

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

The IGF-IR(Phospho Tyr1161) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of insulin-like growth factor 1 receptor (IGF-IR) phosphorylated at tyrosine 1161. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the phosphorylated form of IGF-IR.

The insulin-like growth factor 1 receptor plays a crucial role in cellular growth, proliferation, and survival. Phosphorylation of tyrosine 1161 is a key event in the activation of IGF-IR signaling pathway, which is implicated in various physiological and pathological processes, including cancer development and progression.

The IGF-IR(Phospho Tyr1161) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated IGF-IR in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The IGF-IR(Phospho Tyr1161) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the IGF-IR(Phospho Tyr1161) Polyclonal Antibody is a valuable tool for investigating the role of IGF-IR phosphorylation in various biological processes. Its high specificity, sensitivity, and versatility make it an essential component of any study aiming to elucidate the molecular mechanisms underlying IGF-IR signaling.