IFN-alpha/beta R alpha(Phospho Tyr466) Polyclonal Antibody

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases| which in turn phosphorylate several proteins| including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

The IFN-alpha/beta R alpha(Phospho Tyr466) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the IFN-alpha/beta receptor alpha subunit phosphorylated at tyrosine 466. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

The IFN-alpha/beta receptor alpha subunit plays a crucial role in the cellular response to interferon-alpha and interferon-beta, which are important cytokines involved in immune response regulation. Phosphorylation of tyrosine 466 on the receptor alpha subunit is a key event in the activation of downstream signaling pathways, leading to the induction of antiviral and immunomodulatory responses.

This polyclonal antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of the phosphorylated IFN-alpha/beta receptor alpha subunit.

The IFN-alpha/beta R alpha(Phospho Tyr466) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and versatility, the IFN-alpha/beta R alpha(Phospho Tyr466) Polyclonal Antibody is an indispensable tool for researchers studying the molecular mechanisms underlying interferon signaling pathways and their role in immune response regulation.