3HAO Polyclonal Antibody

3-Hydroxyanthranilate 3|4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.

The 3HAO Polyclonal Antibody is a highly specific and reliable tool for the detection and quantification of 3-hydroxyanthranilic acid oxidase (3HAO) in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, making it an ideal choice for researchers in the field of biochemistry and molecular biology.

The 3HAO Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested against a wide range of antigens to guarantee its specificity and reliability. This antibody recognizes the 3HAO protein with high affinity, enabling accurate and precise quantification of its expression levels.

This antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in both human and animal samples, allowing for versatile experimental designs. The 3HAO Polyclonal Antibody is compatible with a variety of detection systems and can be used in combination with other antibodies for multiplexing experiments.

In addition to its exceptional performance, this antibody is provided in a convenient and user-friendly format. It is supplied as a liquid formulation, ready for immediate use without the need for reconstitution or additional preparation steps. The 3HAO Polyclonal Antibody is available in different sizes to accommodate various experimental needs.

Overall, the 3HAO Polyclonal Antibody is a valuable tool for researchers studying the role of 3HAO in various biological processes. Its high specificity, sensitivity, and ease of use make it an indispensable asset in the laboratory, facilitating accurate and reliable data generation.