VASP(Phospho Ser157) Polyclonal Antibody

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein| family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

The VASP(Phospho Ser157) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of VASP protein phosphorylated at Ser157. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

The VASP protein plays a crucial role in actin filament dynamics and cell motility. Phosphorylation of VASP at Ser157 has been implicated in various cellular processes, including cell adhesion, migration, and invasion. Therefore, the ability to accurately measure the phosphorylation status of VASP at Ser157 is of great importance in understanding the underlying mechanisms of these processes.

This polyclonal antibody exhibits exceptional specificity towards the phosphorylated form of VASP at Ser157, enabling precise and reliable detection in various experimental settings. It has been extensively validated using a range of techniques, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring its suitability for diverse applications.

The VASP(Phospho Ser157) Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, ensuring stability and ease of handling. Additionally, it is available in different sizes to accommodate varying experimental needs.

With its high specificity, sensitivity, and reliability, the VASP(Phospho Ser157) Polyclonal Antibody is an indispensable tool for researchers studying VASP phosphorylation and its implications in cellular processes. Its exceptional performance and ease of use make it an ideal choice for both basic research and clinical applications.