COTL1 Rabbit Polyclonal Antibody

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin| and also interacts with 5-lipoxygenase| which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region| the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.

The COTL1 Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of COTL1 protein expression in various biological samples. This antibody has been rigorously validated for its performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

COTL1, also known as Coactosin-like protein 1, is a member of the actin-binding protein family and plays a crucial role in actin filament dynamics and cytoskeletal organization. It is involved in various cellular processes, including cell migration, adhesion, and invasion. Dysregulation of COTL1 expression has been implicated in several diseases, such as cancer and neurodegenerative disorders.

The COTL1 Rabbit Polyclonal Antibody has been developed using high-quality rabbit polyclonal antibodies that specifically recognize COTL1 protein. It exhibits excellent sensitivity and specificity, ensuring reliable and accurate results. The antibody has been extensively tested and validated using a wide range of cell lines and tissue samples, guaranteeing its suitability for diverse experimental settings.

In IHC applications, the COTL1 Rabbit Polyclonal Antibody demonstrates strong and specific staining of COTL1 protein in formalin-fixed, paraffin-embedded tissue sections. It enables precise localization and visualization of COTL1 expression within the cellular context. The antibody also exhibits robust performance in IF, allowing for the detection of COTL1 protein in cultured cells and tissue sections with high resolution and minimal background signal.

Furthermore, the COTL1 Rabbit Polyclonal Antibody is compatible with western blotting, enabling the detection and quantification of COTL1 protein in cell lysates and tissue extracts. It exhibits a clean and specific band pattern, facilitating accurate analysis and comparison of protein expression levels.

Overall, the COTL1 Rabbit Polyclonal Antibody is a reliable and versatile tool for researchers studying COTL1 protein expression and its functional implications. Its high specificity, sensitivity, and compatibility with multiple applications make it an essential component of any comprehensive research study in the field of actin dynamics and cytoskeletal organization.