Trk A(Phospho Tyr496) Polyclonal Antibody

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that| upon neurotrophin binding| phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain| anhidrosis| self-mutilating behavior| mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found| but only three have been characterized to date.

The Trk A(Phospho Tyr496) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Trk A protein phosphorylated at Tyr496. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

Trk A, also known as tropomyosin receptor kinase A, is a receptor tyrosine kinase that plays a crucial role in the development and maintenance of the nervous system. Phosphorylation of Tyr496 in Trk A is a key event in the activation of downstream signaling pathways involved in neuronal growth, survival, and differentiation.

The Trk A(Phospho Tyr496) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It exhibits minimal cross-reactivity with non-phosphorylated Trk A and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended to store the antibody at -20°C for long-term use to maintain its stability and activity.

With its exceptional specificity and sensitivity, the Trk A(Phospho Tyr496) Polyclonal Antibody is an indispensable tool for researchers studying the role of Trk A phosphorylation in neuronal development, neurodegenerative diseases, and other related fields.