CNOT6 Rabbit Polyclonal Antibody

This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes| including miRNA-mediated repression| mRNA degradation| and transcriptional regulation.

The CNOT6 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CNOT6 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CNOT6 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The CNOT6 Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes a single band of approximately 60 kDa in Western blot analysis of human, mouse, and rat cell lysates. In addition, it shows strong staining of CNOT6 protein in formalin-fixed, paraffin-embedded human tissues, indicating its suitability for use in immunohistochemistry.

This antibody is an essential tool for researchers studying the role of CNOT6 protein in various biological processes, including RNA metabolism, gene expression, and cell proliferation. Its high specificity and sensitivity make it an ideal choice for detecting CNOT6 protein in complex biological samples. The CNOT6 Rabbit Polyclonal Antibody is available in various sizes and formats to meet the needs of different research applications.