TAL1/2 (Acetyl Lys221/Acetyl Lys222/Acetyl Lys36/Acetyl Lys37) Polyclonal Antibody

alternative products:The splicing pattern is cell-lineage dependent|disease:A chromosomal aberration involving TAL1 may be a cause of some T-cell acute lymphoblastic leukemias (T-ALL). Translocation t(1;14)(p32;q11) with T-cell receptor alpha chain (TCRA) genes.|The helix-loop-helix domain is necessary and sufficient for the interaction with DRG1.|Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation.|PTM:Phosphorylated on serine residues. Phosphorylation of Ser-122 is strongly stimulated by hypoxia.|PTM:Ubiquitinated; subsequent to hypoxia-dependent phosphorylation of Ser-122| ubiquitination targets the protein for rapid degradation via the ubiquitin system. This process may be characteristic for microvascular endothelial cells| since it could not be observed in large vessel endothelial cells.|Contains 1 basic helix-loop-helix (bHLH) domain.|subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms heterodimers with TCF3. Binds to the LIM domain containing protein LMO2 and to DRG1. Can assemble in a complex with LDB1 and LMO2. Component of a TAL-1 complex composed at least of CBFA2T3| LDB1| TAL1 and TCF3.|tissue specificity:Leukemic stem cell.|

Introducing the TAL1/2 (Acetyl Lys221/Acetyl Lys222/Acetyl Lys36/Acetyl Lys37) Polyclonal Antibody, a highly specialized and meticulously crafted product designed to cater to the discerning needs of the scientific community. This antibody, derived from polyclonal sources, exhibits exceptional specificity and sensitivity, making it an invaluable tool for various research applications.

The TAL1/2 Polyclonal Antibody has been meticulously engineered to target and bind to the acetylated forms of Lysine residues at positions 221, 222, 36, and 37 within the TAL1/2 protein. This antibody's unique ability to recognize and interact with these specific acetylated sites enables researchers to delve deeper into the intricate mechanisms and functions of TAL1/2.

With its superior affinity and selectivity, this antibody offers researchers an unprecedented opportunity to explore the role of TAL1/2 in various biological processes, including gene regulation, chromatin remodeling, and cellular differentiation. Its exceptional performance ensures accurate and reliable results, facilitating groundbreaking discoveries and advancements in the field of molecular biology.

The TAL1/2 Polyclonal Antibody is manufactured using state-of-the-art techniques and stringent quality control measures, guaranteeing its consistency and reliability. Each batch undergoes rigorous testing to ensure optimal performance, providing researchers with the utmost confidence in their experimental outcomes.

Furthermore, this antibody is compatible with a wide range of applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its versatility allows for seamless integration into various experimental protocols, catering to the diverse needs of researchers across different disciplines.

In summary, the TAL1/2 (Acetyl Lys221/Acetyl Lys222/Acetyl Lys36/Acetyl Lys37) Polyclonal Antibody represents a pinnacle of scientific innovation and precision. Its exceptional specificity, sensitivity, and versatility make it an indispensable tool for researchers seeking to unravel the complexities of TAL1/2 and its associated biological processes. Trust in this antibody to elevate your research endeavors to new heights and pave the way for groundbreaking discoveries.