Tak1(Phospho Thr187) Polyclonal Antibody

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP)| and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1| this protein forms a kinase complex including TRAF6| MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK| MAP2K4/MKK4| and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

The Tak1(Phospho Thr187) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Tak1 protein phosphorylated at Thr187 residue. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The Tak1 protein plays a crucial role in various cellular processes, including immune response, inflammation, and cell survival. Phosphorylation of Tak1 at Thr187 has been implicated in the regulation of its activity and downstream signaling pathways. Therefore, the ability to accurately detect and quantify the phosphorylation status of Tak1 at Thr187 is of great importance in understanding its functional role in different biological contexts.

The Tak1(Phospho Thr187) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of phosphorylated Tak1 at Thr187. It has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. The antibody demonstrates minimal cross-reactivity with non-phosphorylated Tak1 and other related proteins, ensuring reliable and accurate results.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The Tak1(Phospho Thr187) Polyclonal Antibody is compatible with a wide range of applications, making it an invaluable tool for researchers studying Tak1 signaling pathways and its involvement in various physiological and pathological processes.

In summary, the Tak1(Phospho Thr187) Polyclonal Antibody is a highly reliable and specific reagent that enables the detection and analysis of phosphorylated Tak1 at Thr187. Its exceptional performance and versatility make it an essential tool for researchers in the field of cellular signaling and molecular biology.