Stat6(Phospho Tyr641) Polyclonal Antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L)| which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells| expression of cell surface markers| and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

The Stat6(Phospho Tyr641) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Stat6 at Tyr641 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Stat6, also known as signal transducer and activator of transcription 6, plays a crucial role in the regulation of immune responses and cellular differentiation. Phosphorylation of Stat6 at Tyr641 residue is a key event in the activation of its signaling pathway, leading to the transcriptional activation of various genes involved in immune response and inflammation.

The Stat6(Phospho Tyr641) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Stat6 in various biological samples.

This antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The product is stored at -20°C, ensuring long-term stability and preserving its activity.

In summary, the Stat6(Phospho Tyr641) Polyclonal Antibody is a highly reliable and efficient tool for the detection and quantification of phosphorylated Stat6 at Tyr641 residue. Its high specificity, sensitivity, and versatility make it an ideal choice for researchers and scientists working in the fields of immunology, cell biology, and inflammation research.