Stat5a(Phospho Ser780) Polyclonal Antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by| and mediates the responses of many cell ligands| such as IL2| IL3| IL7 GM-CSF| erythropoietin| thrombopoietin| and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L)| which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been

The Stat5a(Phospho Ser780) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Stat5a at Serine 780. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Stat5a, a member of the signal transducer and activator of transcription (Stat) family, plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. Phosphorylation of Stat5a at Serine 780 is known to be a key regulatory event in its activation and subsequent transcriptional activity.

The Stat5a(Phospho Ser780) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Stat5a in a wide range of sample types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The product is accompanied by a detailed datasheet, containing comprehensive information on its recommended usage, storage conditions, and handling instructions.

In summary, the Stat5a(Phospho Ser780) Polyclonal Antibody is a valuable tool for researchers and scientists involved in studying the role of Stat5a phosphorylation in cellular signaling pathways. Its high specificity, sensitivity, and versatility make it an indispensable asset in various research applications.